ASSOCIATION OF OSTEOCAICIN GENE POLYMORPHISM WITH BONE MASS IN CHINESE PREMENARCHE GIRLS / 营养学报
Acta Nutrimenta Sinica
;
(6)2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-560698
ABSTRACT
Objective:
To assess the proportion of genotypes of osteocalcin gene polymorphism, and to investigate if the polymorphism of osteocalcin gene is associated with BMD in Chinese premenarche girls.Methods:
152 healthy premenarche girls of Han ethic (9-11.5y) were recruited. BMD and BMC at the lumber spine (L1-L4), proximal femur, and total body were measured by DXA; PCR-RFLP was used to amplify the polymorphisms of the osteocalcin gene.Results:
The proportion of genotype of OC gene polymorphism were 5.26% HH,, 36.84% Hh, and 58.90% hh, respectively. Significant differences were observed in BMD and BMC at the total body, and BMD at the L1-L4 lumber spine and femur neck among subjects with different genotypes (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Acta Nutrimenta Sinica
Ano de publicação:
2004
Tipo de documento:
Artigo
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