Relationship between plasma vitamin D level and delayed childhood rickets / 解放军医学杂志

ABSTRACT

Objective To investigate the relationship between vitamin D level in plasma and concomitant symptoms in children over 4 years of age. Methods Radioimmunoassay was employed to detect the vitamin D level in plasma of 98 children over 4 years of age suffering from monoarticular joint-pain, debility, dizziness and hyperhidrosis. Results Among the 98 cases, 15 cases (rickets) were found to have a vitamin D level of 0-10ng/ml, 26 cases (subclinic rickets) with a level of 10.1-15ng/ml, 55 cases with a level of 15.1-60ng/ml, and the remaining 2 were found to have a level of 61-86ng/ml. A significant positive correlation existed between the low vitamin D level in plasma and the symptoms of joint-pain, debility, dizziness, and hyperhidrosis. Conclusion It is of a diagnostic significance to determine the 25-hydroxyvitanmin D_3 level in plasma to confirm the diagnosis of delayed vitamin D deficiency rickets in children.