The effects of plasma low high-density lipoprotein cholesterol on platelet cytosolic free calcium and release reaction / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-561297
ABSTRACT
Objective To discuss pathogenic effects of low high-density lipoprotein cholesterol(HDL-C)on atherosclerosis and thromboembolism,the influences of HDL-C on platelet cytosolic free calcium concentration([Ca2+]i),platelet release reaction products beta-thromboglobulin(?-TG)and platelet factor 4(PF4)were observed in dyslipoproteinemia patients with low HDL-C.Methods i,?-TG and PF4 were measured by fluorescent probe Fura 2-AM and ELISA skills respectively,in 42 patients with low HDLC(LHDL-C)and 25 healthy controls(CONT).Results Compared with those in CONT group,the platelet[Ca2+]i,?-TG and PF4 were all higher in LHDL-C group(all P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Practical Internal Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo
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