Diagnosis and treatment of malignant rectal gastrointestinal stromal tumor / 中国基层医药

ABSTRACT

Objective To evaluate the diagnosis and treatment of malignant rectal gastrointestinal stromal tumor.Methods The clinical and pathological data of 26 patients with malignant rectal gastrointestinal stromal tu- mor were retrospectively analyzed.Results All the patients underwent operation.In 13 cases Miles operation was done and 3 cases Park operation was done.The 10 patients received Dixon resection.The 3-,5-year survival rate were 73% and,54 %,respectively.The median survival time for 26 patients was 52 months.Immunohistochemical analysis displayed positive reactivity for CD117(96%) and CD34(85%).Conclusion For the malignant rectal gas- trointestinal stromal tumor,the most worthwhile diagnostic criterion was the presence of CD117 and CD34 cells and surgical radical resection is the principal treatment.