Significance of bFGF,FGFR-2 and Hpa expression in gastric precancerous lesions and gastric carcinoma tissues / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-562065
ABSTRACT
Objective To study the expression of basic fibroblast growth factor(bFGF),fibroblast growth factor receptor-2(FGFR-2)and heparanase(Hpa)in the tissues of gastric cancer and precancerous lesions,and to explore its significance in the carcinogenesis and malignant progression of stomach.Methods The expression of bFGF,FGFR-2 and Hpa were detected by immunohistochemistry in 145 cases of paraffin-embedded specimens from different gastric mucosa,including 30 cases of chronic superficial gastritis(CSG),29 of intestinal metaplasia(IM),31 of dysplasia(Dys)and 55 of gastric carcinoma(GC).Results The expression of bFGF and FGFR-2 in CSG group was significantly lower than that of the other three groups(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Practical Internal Medicine
Ano de publicação:
2006
Tipo de documento:
Artigo
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