Comparison of Lactobacillus casei in Stool between Children with Atopic Dermatitis and Normal Controls / 소아알레르기및호흡기학회지

ABSTRACT

PURPOSE: As allergy diseases including atopic dermatitis are increasing lately, many kinds of studies about the cause and the pathogenesis are in progress and the secrets of the of organization intestinal microflora and the relationship with inflammatory are reaction actively being revealed. METHODS: In this study, the subjects included 32 atopic dermatitis patients and 23 normal controls who visited the allergy clinics of the pediatrics department in Soonchunhyang University Hospital from June to October, 2003. Lactobacillus casei were cultured and counted. And serum total IgE, IgA and AST/ALT were examined. Also, the differences in lactobacillus counts between the atopic dermatitis patients and normal controls were analyzed. RESULTS: We were not able to find out a statistically significant differences between the atopic dermatitis patients and the control group. We were able to find out a statistically significant inverse correlation of serum total IgE and the number of Lactobacillus casei. CONCLUSION: The significant inverse correlations of serum total IgE and the number of Lactobacillus casei are expected to contribute to precognition and treatment of atopic dermatitis. It is hoped that more researches on the relationship between atopic dermatitis and intestinal flora should be carried out in the future.