Development of hepatocyte transplantation / 国际生物医学工程杂志

ABSTRACT

As a safe and effective treatment method of fulminic hepatic failure and end stage liver disease, hepatocyte transplantation has been widely verified in many animal experiment and clinical research. It has many advantages. For instances, It is safe and easy to perform. It causes little trauma and is convenient for retransplantation. The hepatocytes are less immunogenetic and the cells from one donor liver can be used for several patients, and so on. The cell source, route of transplantation, theoretical basis and clinical application of the method are reviewed in this paper.