Gelatinized starch is more feasible for starch tolerance test / 中国药理学通报

ABSTRACT

Aim To study the effect of gelatinized starch on starch tolerance test.Methods Acarbose with gelatinized starch or ungelatinized starch was administered to ICR mice by gavage,and blood samples were collected at 30,60 and 120 minutes after treatment to measure blood glucose levels,whose rising percentage calculated at 30 min and AUC in every group.Results Compared with the ungelatinizedstarch group,blood glucose levels at 30 and 60 minutes after starch loading were significantly elevated in the gelatinized-starch group.Acarbose drastically flatted the elevation of blood glucose after gelatinized-starch load,but it had little effect on the ungelatinized-starch test.Conclusion It is more feasible to use gelatinized starch to carry out starch tolerance test than to use ungelatinized starch.