Effect of total flavonoids of Astragalus on apoptosis of cultured bovine retinal capillary pericytes under high glucose / 中华中医药杂志
Article
em Zh
| WPRIM
| ID: wpr-563090
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WPRO
ABSTRACT
Objective: To study the effects of total flavonoids of Astragalus on apoptosis of bovine retinal capillary pericytes(BRPs) under high glucose.Methods: The third generation of nearly symphysic bovine retinal vessel pericytes cultivated in vitro were divided into normal control group,high glucose group,and Astragalus total flavonoids groups(0.25,0.5,1.0,2.0 mg/ml) at random.After being incubated for 6 days,apoptosis of BRPs were detected by TUNEL method.TBA method was used to detect the contents of MDA.Xanthine oxidase method was used to detect the SOD activities.Results: Compared with high glucose group,the apoptosis,MDA contents,SOD activity,MDA content/SOD activity of BRPs reduced markedly in total flavonoids of Astragalus groups(0.5,1.0,2.0mg/ml)(P
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Índice:
WPRIM
Idioma:
Zh
Revista:
China Journal of Traditional Chinese Medicine and Pharmacy
Ano de publicação:
2005
Tipo de documento:
Article