By Fluorescence Quantitative Polymerase Chain Reaction CMV Viral Hepatitis in the Application / 医学研究杂志

ABSTRACT

Objective To investigate the fluorescence quantitative polymerase chain reaction(FQ-PCR)in the giant cell viral hepatitis in value.Methods 50 cases of serum IgM HCMV-positive patients with hepatitis and 25 cases of healthy people to do the control group respectively serum FQ-PCR detection of its content HCMVDNA its detection rate compared with the liver function and the relationship.Results Of 50 cases of serum IgM HCMV-positive patients with hepatitis HCMVDNA>103Copies/ml those 35 cases,HCMVDNA positive to the negative group than HCMVDNA serum total bilirubin(TBiL)alanine aminotransferase(ALT)aspartate aminotransferase(AST)to the high statistics P <0.05 the difference was significant.25 cases of healthy control group and HCMVDNA HCMV-IgM were negative.Conclusions FQ-PCR in cytomegalovirus infection with hepatitis reliable early diagnosis of the characteristics through HCMVDNA content of the clinical evaluation of drug efficacy has certain clinical value.