Mitochondrial DNA Polymorphism Associated with Longevity in Taklimakan Desert Uygur Centenarians / 医学研究杂志
Journal of Medical Research
;
(12)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-563691
ABSTRACT
Objective Sequence variations in mitochondrial DNA genes have been found to influence successful aging and longevity. The aim of this study was to examine whether mitochondrial DNA polymorphisms influenced the longevity in Chinese Uygur population.Methods We genotyped the mt5178A and mt10398G in 277 sampels representing three age group (centenarian, n=65; longevity, n=100; controls, n=112) from Taklimakan desert Uygur centenarians,China Results The distribution frequency of the 5178A in the centenarian (51/65, 78.5%) is slightly higher than in those of controls (63/112,56.3%,P=0.0029) . The frequency of the 10398G were significantly higher among the centenarian(47/65,72.3%)and longevity(68/100,68%) in comparison to the controls(60/112,53.6%,P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Medical Research
Ano de publicação:
2006
Tipo de documento:
Artigo
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