Expression of periostin and the effect of hydrocortisone on it in human fibroblasts of scar / 北京大学学报(医学版)
Article
em Zh
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| ID: wpr-563709
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WPRO
ABSTRACT
Objective:To probe into the role of periostin in the formation of scars and investigate its reaction to hydrocortisone.Methods: Primary fibroblasts were cultured in vitro,then RT-PCR and immunocytochemical technique were used to examine the expressions of mRNA and preotein of periostin respectively in 24 samples of keloid fibroblasts(KFb),hypertrophic scar fibroblasts(HFb) and normal skin fibroblasts(SFb).Results: The mRNA levels of periostin in KFb(1.645?0.549) and HFb(1.084?0.396) were both higher than that in SFb(0.274?0.215,P
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WPRIM
Idioma:
Zh
Revista:
Journal of Peking University(Health Sciences)
Ano de publicação:
2004
Tipo de documento:
Article