Advances in uveitis research in China / 眼科

ABSTRACT

Studies on uveitis have gained a great achievement during recent years in China.A number of studies have provided evidences to support the opinion that both Th1 and Th17 cells are involved in the pathogenesis of uveitis.Increased resistance of lym- phocytes to apoptosis due to disturbed expression and Fas/FasL,decreased frequencies and function of CD4+CD25high T cells,in- creased leptin and polymorphisms of certain Cytokines are also involved in the development or recurrence of uveitis.Clinical studies have revealed distinctive features of Vogt-Koyanagi-Harada syndrome and Fuchs syndrome in Chinese patients.Studies using Laser flare-cell meter and multifocal electroretinography have greatly contributed to our understanding of the pathophysiological alterations of uveitis.A number of papers on uveitis have been published in the top journels of ophthalmology in the world.However,it is worthwhile to point that there are very few doctors engaged in uveitis study and that diagnosis and treatment of uveitis should be further improved in future in China.