A systematic review of eradicating helicobacter pylori with ranitidine bismuth citrate / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
; (12)2001.
Article
em Zh
| WPRIM
| ID: wpr-564950
Biblioteca responsável:
WPRO
ABSTRACT
Objective To systematically review the Helicobacter pylori eradication efficacy with ranitidine bismuth citrate(RBC) and two antibiotics,and to conduct a meta-analysis of randomized clinical trials comparing the efficacy of proton pump inhibitor(PPI)vs RBC with two antibiotics for 1 week.Methods Selection of studies:studies evaluating RBC plus two antibiotics were considered.For the meta-analysis,randomized controlled trials comparing PPI vs.RBC plus two antibiotics for 1 week were included.Data Source:RCTs were identified from CBM,handsearching,and personal contact with pharmaceutical companies.Inclusion criteria:data were extracted independently by two reviewers.The methodological quality of trials was assessed by the Jadad-scale.Statistics analysis was managed by using RevMan 4.2.Results Twelve randomized clinical trials including 1254 patients were included.The meta-analysis showed comparable efficacy with RBC and PPI (OR=1.30,95% CI:0.94~1.81,P=0.12).Conclusion The efficacy of RBC and PPI-based triple regimens were comparable.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
/
Systematic_reviews
Idioma:
Zh
Revista:
Chinese Journal of Practical Internal Medicine
Ano de publicação:
2001
Tipo de documento:
Article