Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs
Journal of Veterinary Science
;
: 123-126, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-56502
ABSTRACT
Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tecido Adiposo
/
Doença Aguda
/
Resultado do Tratamento
/
Descompressão Cirúrgica
/
Transplante de Células-Tronco Mesenquimais
/
Doenças do Cão
/
Degeneração do Disco Intervertebral
/
Percepção da Dor
/
Deslocamento do Disco Intervertebral
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2016
Tipo de documento:
Artigo
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