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The effects of alanyl-glutamine dipeptide-enriched parenteral nutrition on outcome in radiation enteritis rats / 肠外与肠内营养
Parenteral & Enteral Nutrition ; (6)1997.
Artigo em Chinês | WPRIM | ID: wpr-565200
ABSTRACT

Objective:

To investigate the impact of alanyl-glutamine(Ala-Gln) on outcome in radiation enteritis rats.

Methods:

Male SD rats(n=70)were separated randomly into four groups control group(n=10),AR+pseudosurgery group(n=20),AR+TPN group(n=20) and AR+TPN+Ala-Gln group(n=20).Rats were observed for mortality,changs of body weight,villous hight and area,the bcteriral translocation(BT)in mesenteric lymph nodes(MLNs),liver,spleen and peritoneal cavity.Serum TNF-? and sIL-2R level were determined by sandwich ELISA.

Results:

When Ala-Gln was administered in radiation enteritis rat,the mortality,body weight loss and bacterial translocation were decreaded,the villous hight and area was increased and the TNF-? and sIL-2R levels were reduced.

Conclusion:

Parenteral Ala-Gln nutrition can improves the results of radiation enteritis rats.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Parenteral & Enteral Nutrition Ano de publicação: 1997 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Parenteral & Enteral Nutrition Ano de publicação: 1997 Tipo de documento: Artigo