Collagen crosslinking with ultraviolet A-light and riboflavin—hope of keratoconus / 眼科

ABSTRACT

Collagen crosslinking by ultraviolet A-light and riboflavin is an effective means for increasing corneal rigidity and preventing the progression of keratoconus.Visual acuity can be improved slightly.The maximum effect of the treatment locates in the anterior 300-340?m of the cornea.No statistically significant change is found for endothelial cell density.With more long-term research, prophylactic treatment of keratoconus at the early stage might become possible,preventing the development of keratoconus and additional refractive correction can be realized.