Relationship of the sensitivity of colon carcinoma cells to gefitinib and the expressions of MET,IGFR-1? and IGF-Ⅱ / 解放军医学杂志

ABSTRACT

0.05).IGFR-1? expressed in all the 6 cell lines,with the highest expression in SW480(P0.05),but a gefitinib-induced and dose-dependent increase in p-IGFR-1?,not IGFR-1?,expression was observed in HT29 cells(P0.05),but the expression of IGFR-1? was higher in HCT116 than in Lovo and HT29(P