The Influence of LPS and PDTC on IL -1? Concentration in Endometriai Cell Culture Supernatant / 医学研究杂志

ABSTRACT

Objective To learn the influence of density of LPS and LPS + PDTC on the concentration of IL -1? of endometrial cells. Method We used LPS and LPS + PDTC to intervene normal and endometriosis patients, and obtain cultivate supernatant,then detected the concentration density of IL - 1?with ELISA. Result The of IL - 1? had no statistical signifiance in normal endometrial cells, but there was notable change in eutopic and ectopic endometrial cells. Conclusion Activating and refrainning NF -?B through LPS and PDTC, then decteting the change of the ancentration of IL - 1?, understanding the relation between NF -?B and endometriosis are all important in pathogenesis.