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Clinical study of protective effects and function regulations of piperazine ferulate tablet on traumatic vascular endothelial cells in type 2 diabetes mellitus / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics ; (12)2000.
Artigo em Chinês | WPRIM | ID: wpr-566949
ABSTRACT

AIM:

To investigate the therapeutic protective effects and function regulations of conventional antidiabetic treatment plus piperazine ferulate tablet on traumatic vascular endothelial cells in type 2 diabetes mellitus.

METHODS:

80 patients were randomly divided into the treating group(n=37)and the control group(n=43).Conventional antidiabetic treatment plus piperazine ferulate was given to the treating group,and the control group was treated with conventional antidiabetic treatment plus vitamin C every day,and all the patients were treated with 4 weeks.The levels of fasting blood glucose(FBG),glycosylated hemoglobin A1C(Hb A1C),circulating endothelial cell(CEC),serum lipid peroxide(LPO),endothelin(ET)、nitric oxide(NO),tissue-plasminogen activator(t-PA)were determined during the therapeutic period.

RESULTS:

After 4 weeks of treatment,the levels of serum CEC,LPO and ET were lower in the treating group than those in the control group(P

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Clinical Pharmacology and Therapeutics Ano de publicação: 2000 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Clinical Pharmacology and Therapeutics Ano de publicação: 2000 Tipo de documento: Artigo