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Effect of Anlv Capsule on sodium ion channels in ventricular myocytes of guinea pig / 中华中医药杂志
China Journal of Traditional Chinese Medicine and Pharmacy ; (12)2005.
Artigo em Chinês | WPRIM | ID: wpr-567169
ABSTRACT

Objective:

To observe the effect of Aalv Capsule on sodium current in guinea pig ventricular myocytes(INa)for exploring the mechanism of its anti-premature beats.

Methods:

Whole-cell patch-clamp recording technique was used to record the Aalv Capsule for a single cell of sodium currents in guinea pig ventricular myocytes.

Results:

There was dose-dependent of Aalv Capsule in block of sodium currents and had a certain amount of use-dependent and time-dependent.

Conclusion:

The role of Aalv Capsule in blocking sodium current block was one of the mechanisms of its in bearing premature.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: China Journal of Traditional Chinese Medicine and Pharmacy Ano de publicação: 2005 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: China Journal of Traditional Chinese Medicine and Pharmacy Ano de publicação: 2005 Tipo de documento: Artigo