The Study of SEB/OVA Allergic Rhinitis Mice Model / 医学研究杂志
Journal of Medical Research
; (12)2006.
Article
em Zh
| WPRIM
| ID: wpr-567230
Biblioteca responsável:
WPRO
ABSTRACT
Objective To establish mice modle of allergic rhinitis(AR) and to study the role of Staphylococcal enterotoxin B(SEB) and ovalbumin(OVA) in the modle.Methods Forty Balb/c mice were evenly randomized into OVA group,SEB group,OVA+SEB group and normal sodium group and AR modle was established.The symptom scores,total serum IgE concentration,IL-4 concentration were analyzed by factorial design.Meanwhile,the morphology change of nasal mucosa was observed.Results The symptom scores in OVA group,SEB group,OVA+SEB group and normal sodium group were 6.80?1.03,0.90?0.99,0.70?0.82,0.60?0.70 respectirely.The interaction of OVA and SEB had statistical significance(P
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Índice:
WPRIM
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Medical Research
Ano de publicação:
2006
Tipo de documento:
Article