Pharmacological management of migraine / 中国实用内科杂志

ABSTRACT

Pharmacological management of migraine should be evidence-based and individualized,combined with patient's education and non-pharmacological management.For acute therapy,simple or combination analgesics (non-steroidal anti-inflammatory drugs) or migraine specific drugs (ergotamines and triptans) are recommended and should be administrated following the concept of stratification or stepwise treatment.For preventive therapy,flunarizine,antidepressant (amitriptyline),antiepileptics (valproic acids and topiramate),and beta-blockers (propranolol and metoprolol) are drugs of first choice and should be chosen individually.Prophylaxis therapy should be evaluated for 4～8 weeks and last for 3～6 months whenever it is effective.