HISTOLOGICAL AND HISTOCHEMICAL CHANGES OF GRANULAR CONVOLUTED TUBULES OF SUBMANDIBULAR GLAND DURING LIVER REGENERATION FOLLOWING PARTIAL HEPATECTOMY OF RATS / 解剖学报

ABSTRACT

50 adult rats divided into 3 groups, i. e. partial hepatectomy, sham-operation and normal control groups. The submandibular glands (SMG) were removed at different intervals (1-14 days) after operation, and stained with histological and histochemical method. On the 1-3 days after operation, especially on 3 days, some changes were found in granular convoluted tubule (GCT) cells of SMG. The secretory granules in the GCT cells were decreased in number. The reactions of PAS, -SS- group, PTAH were weaker than those of the sham-operation group, but the reactions of content in tubule system of SMG were raised. The reaction of SDH was stronger than those of the sham-operation group and the activities of NE and AcP decreased. After 7 days all the changes gradually restored, except the activities of ASDH increased and NE decreased continuously. After 14 days, all the changes became nearly normal. In addition, the reactions of RNA, G6Pase and 5-Nase in GCT cells of hepatectomized rats did not show apparent changes. The results suggested that, the changes of SMG GCT cells following partial hepatectomy seem, to be closely related with regenerative process of liver.