Docetaxel-Induced Fatal Interstitial Pneumonitis in a Patient with Castration-Resistant Prostate Cancer
Korean Journal of Urology
;
: 371-374, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-56894
ABSTRACT
A 69-year-old man with castration-resistant prostate cancer (CRPC) received docetaxel and a corticosteroid. After the third cycle of docetaxel administration, he presented with dyspnea, cough, sputum, and fever of 39.2degrees C. The chest X-ray and chest computed tomography (CT) revealed a diffuse reticulonodular shadow in both lungs, which suggested interstitial pneumonitis. Initially, we used empiric broad-spectrum antibiotics and high-dose corticosteroids. However, his condition progressively became worse and he was transferred to the intensive care unit, intubated, and placed on mechanical ventilation. He died 4 days after hospital admission. Here we report this case of fatal interstitial pneumonitis after treatment with docetaxel for CRPC. We briefly consider docetaxel-induced pneumonitis to make physicians aware of the possibility of pulmonary toxicity so that appropriate treatment can be begun as soon as possible.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonia
/
Próstata
/
Neoplasias da Próstata
/
Respiração Artificial
/
Escarro
/
Tórax
/
Corticosteroides
/
Doenças Pulmonares Intersticiais
/
Tosse
/
Taxoides
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Urology
Ano de publicação:
2012
Tipo de documento:
Artigo
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