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Protective Effect of Total Peaony Glycoside on Calium-Overloading Injury of Nerve Cells in Rat Cortex / 中药新药与临床药理
Traditional Chinese Drug Research & Clinical Pharmacology ; (6)1993.
Artigo em Chinês | WPRIM | ID: wpr-569862
ABSTRACT

Objective:

To investigate the protective effect and mechanism of total peaony glycoside (TPG) on calium overloading injury of nerve cells in rat models.

Methods:

The nerve cells of cerebral cortex of primary rats were subject to tissue culture,and the calcuim-overloading injury models were induced by caffeine,KCl and NMDA respectively.

Results:

TPG possessed obvious protective effects on the nerve cells in rat models, increased the number of survival nerve cells and reduced the content of LDH released nerve cells.

Conclusion:

TPG can protect rat nerve cells with calium-overloading injuriy.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Traditional Chinese Drug Research & Clinical Pharmacology Ano de publicação: 1993 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Traditional Chinese Drug Research & Clinical Pharmacology Ano de publicação: 1993 Tipo de documento: Artigo