The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis
Annals of Surgical Treatment and Research
;
: 17-22, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-57053
ABSTRACT
PURPOSE:
The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses.METHODS:
Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats and assigned to an oxygen/nitrous oxide mixture with a fraction of inspired oxygen of 30% in groups 1 and 3 and 80% in groups 2 and 4. The measurements of perianastomotic tissue oxygen pressure, bursting pressure, level of hydroxyproline were evaluated and compared in all groups.RESULTS:
The perianastomotic tissue oxygen pressures, bursting pressures and levels of hydroxyproline were identified as significantly high in groups 2 and 4, administered a fraction of inspired oxygen of 80%, compared to groups 1 and 3, administered a fraction of inspired oxygen of 30%.CONCLUSION:
Perioperative supplemental oxygen contributes positively to the anastomotic healing.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxigênio
/
Ventilação
/
Ratos Wistar
/
Hidroxiprolina
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Annals of Surgical Treatment and Research
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS