The susceptibility of Plasmodium falciparum to pyrimethamine and cycloguanil in a malarial area of Quang Binh
Journal of Preventive Medicine
;
: 48-53, 2004.
Artigo
em Vietnamita
| WPRIM
| ID: wpr-5708
ABSTRACT
PCR-RFLP and DNA sequencing techniques were used for Pyrimethamine (PYR) and Cycloguanil (CYC) resistant mutations. The study results showed that 46 of 58 Plasmodium falciparum isolates were genotype resistant to pyrimethamine (79.31%). Thirty-one isolates were taken in vitro microscopic examination and revealed that 26 of 31 isolates were PYR resistance (83.87%) and 6 of 31 isolates of CYC resistance (19.35%). The resistant levels of these isolates were related to the mutations in DHFR genes
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasmodium falciparum
/
Pirimetamina
/
Proguanil
/
Malária
Idioma:
Vietnamita
Revista:
Journal of Preventive Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo
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