Experimental study of electrochemotherapy on implanted liver tumor cells apoptosis of rats / 介入放射学杂志

ABSTRACT

Objective To compare the effects of electrochemotherapy (EChT) on implanted liver tumor cells apoptosis of rats.Methods Immediate cancerous ascitis injection method was used for the formation of rats liver tumor model and then followed by rats liver tumor treatment with EChT. Tumor size, necrosis and apoptosis indexes were observed after one week by imaging or pathologic method. The results were compared with those of control group. Results Before EChT, rats liver tumor volume appeared as (100?6)mm 3 and turned to be (125?10)mm 3 one week after EChT, which were significantly smaller than those of the control group [(190?11)mm 3], P