Determination of Schizandrin, Deoxyshizandrin and ?-Schizandrin in Jiangtang Soft Capsule by HPLC / 中药新药与临床药理
Article
em Zh
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| ID: wpr-571507
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WPRO
ABSTRACT
Objective To establish a method for the determination of schizandrin, deoxyschizandrin and ?-schizandrin in Jiangtang soft capsule. Methods The sample was extracted by methanol. The chromatographic conditions were: a gradient mobile phase of methanol-water(65: 35)within 0~20 rain and methanol-water(70: 30)within 20~80 min, the wavelength at 250 nm. Results A linear range of schizandrin, deoxyschizandrin and ?-schizandrin was within 0.71 ?g~3.53 ?g(r=0.99998, n=5), 0.19?g~0.95 ?g(r=0.99993, n=5)and 0.36?g~1.80?g(r=0.99997, n=5) and the average recoveries were 100.44%, 98.06% and 101.14% respectively. Conclusion This method is easy, sensitive, specific and accurate for the determination of schizandrin, deoxyschizandrin and ?-schizandrin in Jiangtang soft capsule.
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WPRIM
Idioma:
Zh
Revista:
Traditional Chinese Drug Research & Clinical Pharmacology
Ano de publicação:
2000
Tipo de documento:
Article