DETECTION OF Nogo-A PROTEOLYTIC FRAGMENT DURING CNS INJURY / 解剖学报
Acta Anatomica Sinica
;
(6)2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-572660
ABSTRACT
Objective To detect Nogo-A proteolytic fragment in CNS injury models and investigate its proteolytic mechanism as well as potential functions. Methods Western blot was performed to detect Nogo-A proteolytic fragment after spinal cord transection,brain ischemia and KA-induced cerebral cortex injury in rats. Results We detected Nogo-A proteolytic fragment in spinal cord transection and brain ischemia models,whereas no Nogo-A proteolytic fragment was found in KA-induced cerebral cortex injury model.Conclusion\ CNS mechanical and ischemic injury may induce the degradation of Nogo-A by certain mechanisms.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Idioma:
Chinês
Revista:
Acta Anatomica Sinica
Ano de publicação:
2002
Tipo de documento:
Artigo
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