Study of effect of total peony glucosides on hypergammaglobulinemia in undifferentiated connective tissue disease / 中华风湿病学杂志

ABSTRACT

Objective To observe the effect of total glucosides of peony on hypergammaglobulinemia of undifferentiated connective tissue disease(UCTD). Methods Fifty patients with UCTD were randomly divided into the treat-ment group (total glucosides of peony and hydroxychloroquine and thymosin) (n=30) and the control group (hydroxychloroquine and thymosin) (n=20). The changes between the two groups on hypergammaglobulinemia after treated for 3 months were compared. Results The two groups all had the IgG and IgA decreased, but the treatment group decreased more significantly. In addition, the treatment group had decreased RF. Conclusion Total glucosides of peony can improve the hypergammaglobulinemia of UCTD.