Determination of Camphor,Isoborneol,Borneol,Cinnamaldehyde and Eugenol in Tonglikang Ointment by Gas Chromatography / 中药新药与临床药理

ABSTRACT

Objective To establish a gas chromatography(GC) method for the determination of camphor,isoborneol,borneol,cinnamaldehyde and eugenol in Tonglikang ointment.Methods Polyethylene glycol with 100 %of application concentration was used as stationary liquid phase.GC was equipped with FID detector at 250 ℃and programmed heating method was applied.Results The resolution and the linearity were good with the recovery rate of camphor being 96.21 %(RSD=1.03 %),isoborneol 97.34 %(RSD=0.99 %),borneol 97.07 %(RSD=1.00 %),cinnamaldehyde 96.00 %(RSD=1.37 %),and eugenol 100.99 %(RSD=1.07 %) respectively.Conclusion The method is convenient,rapid and accurate.It can be used to control the quality of Tonglikang ointment.