Effects of scorpion tegument protein on immune function in normal mice / 中草药

ABSTRACT

Objective To study effects of scorpion tegument protein(STP) on immunological function in normal mice and provide experimental data for searching new compounds.Methods Resazurin and MTT assay were used to detect the effects of scorpion tegument water-soluble protein,scorpion tegument keratin protein (STKP) and STP component Ⅱ(STPⅡ) on the transformation of T and B lymphocytes,and NK cell activity in normal mice.Results By ig STP and STKP,the proliferation response of T lymphocyte in murine spleen was higher than that in normal control group,while only there was significant difference between low-dose of STP group compared with the normal control group(P