Effect of Traditional Chinese and Western Medicine for Primary Chronic Glomerular Nephritis: An Observation of 36 Cases / 广州中医药大学学报

ABSTRACT

[Objective] To explore the therapeutic effect of traditional Chinese and western medicine for the treatment of primary chronic glomerular nephritis. [Methods] Seventy-two cases were randomized into two groups by using random number table. Group A ( n = 36) was treated with compound Glucosidorum Tripterygll Totorum Tablets, Jinshuibao Capsules, Compound Sanqi Capsules for oral use, as well as intravenous injection of Huangqi injection apart from routine western medicines, and at the same time given herbal medicine on the basis of syndrome differentiation. Group B ( n = 36) was treated with routine western medicines such as drugs resisting hypertension, diuretics and hormones when necessarily. After a 60-day treatment, the therapeutic effect in the two groups was observed as well as the changes of 24-hour urinary protein, serum total protein (TP) , albumin (Alb), total cholesterol (TC ) , triglyceride (TG) and immunoglobulins (Ig) A and G. [Results] The total effective rate was 94.44% in group A, and 66.67% in group B, the difference being significant (P 0.05). [Conclusion] The effect of traditional Chinese and western medicine for the treatment of primary chronic glomerular nephritis is better than that by using western medicine only.