EXPRESSION OF DENDRITIC CELL MOLECULE MARKER AND ITS RELATION WITH T CELL IN HUMAN BREAST CANCER / 解剖学报

ABSTRACT

Objective To investigate the numbers and distribution of dendritic cells and the expressive intensity of CD1c,S-100,HLA-DR and its relation with T cell in human breast cancer tissues,and to discuss the relationship between dendritic cell(DCs) and developing of breast cancer.The study can provide the experimental data in the further biological therapy of breast cancer. Methods The human breast cancer tissues and relatively normal breast tissues were collected from surgical operation and the samples of 20 patients with breast cancer were analyzed by immunocytochemistry and computer imaging techniques. Results The result showed that the expressive intensity of CD1c,S-100,HLA-DR was dramatically weaker in breast cancer tissues than in those of relatively normal breast tissues(P