EXPRESSION OF COLLAGEN I BY IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION IN RAT HEART / 解剖学报

ABSTRACT

Objective To probe distribution and excreting cells of type I collagen in rat heart. Methods Expression of cardiac collagen I was detected using immunohistochemistry and in situ hybridization. Results Type I collagen was distributed in myocytes,and it encased each cardiac cell.The densities of collagen network in difference cardiac part were of disparity.Type I collagen was all expressed in fibrcyte and smooth muscle cells and endothelial cells in blood vessels of cardiac tissue.Conclusion The type I collagen is a main component of cardiac fibrous network,and its excreting cells are multifocal.