Studies on the Secondary Metabolites of the Soft Coral Sinularia papillosa / 中药新药与临床药理

ABSTRACT

Objective Secondary metabolites of the soft coral were studied to find out the lead compound of the drugs. Methods Compounds from the soft coral Sinularia papillosa were obtained by column chromatography and modern isolation methods and their structures were identified by spectrum of UV,IR,NMR,MS,et al. Results Two white amorphous compounds were obtained from the EtOAc (ethyl acetate) fraction,and their structures were identified as pregn-5,20 -dien-3?-ol-3-O-?-L-fucopyranoside (1) and 1-(17Z-tetracose-nyloxy)-1,2 -propanediol (2) by spectral analysis. Conclusion Two compounds are first isolated from the soft coral genus Sinularia,which will be beneficial for the taxonomy of the soft coral and for biogenesis of steroids.