A Cytogenetic Study of Recurrent Spontaneous Abortion / 대한불임학회지
Korean Journal of Fertility and Sterility
;
: 475-481, 1999.
Artigo
em Coreano
| WPRIM
| ID: wpr-57529
ABSTRACT
OBJECTIVE:
The purpose of this investigation is to determine the frequency of chromosomal or genetic causes of recurrent spontaneous abortion.METHODS:
A cytogenetic study was made in of 921 couples for 13 years from January 1984 to December 1997 in which the woman was ascertained to have had two or more spontaneous abortions at our Cytogenetic Laboratory, Institute of Reproductive Medicine and Population, Seoul National University.RESULTS:
The overall incidence of chromosome anomaly was 80 out of 921 (8.7%). There were 34 cases (3.69%) of reciprocal balanced translocation and 13 cases (1.41%) of Robertsonian translocation. Also 17 cases (1.85%) of inversion and 5 cases (0.54%) of X chromosome mosiacism was observed. In the case of reciprocal balanced translocation, chromosome 8,6,7,13 were preferentially involved over others. And in the case of Robertsonian translocation, chromosome 13 was preferentially involved.CONCLUSION:
Our study demonstrates that cytogenetic analysis is indicated in couples with 2 or more spontaneous abortion and about half of these disorders are reciprocal balanced or Robertsonian translocations.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cromossomo X
/
Cromossomos Humanos Par 13
/
Aborto Espontâneo
/
Características da Família
/
Incidência
/
Medicina Reprodutiva
/
Análise Citogenética
/
Citogenética
/
Seul
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Gravidez
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Korean Journal of Fertility and Sterility
Ano de publicação:
1999
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS