The Association between Urine Albumin to Creatinine Ratio and Osteoporosis in Postmenopausal Women with Type 2 Diabetes
Journal of Bone Metabolism
;
: 1-7, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-57552
ABSTRACT
BACKGROUND:
Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass density and destruction of microstructure, which can lead to an increased risk of fracture. Although many studies have been published about the relationship between end-stage renal disease and osteoporosis, research on the relationship between proteinuria and the prevalence of osteoporosis is still lacking.METHODS:
We assessed 91 postmenopausal women with type 2 diabetes who visited our hospital from January 2009 to January 2012.RESULTS:
Among 91 patients, the prevalence of osteoporosis and osteopenia was 35.2% (32 cases) and 32.9% (30 cases) according to bone mineral density. The patients with microalbuminuria and macroalbuminuria (urine albumin-to-creatinine ratio [UACR] > or = 30) had a significantly higher incidence of osteoporosis compared to subjects with normoalbuminuria (P<0.05).CONCLUSIONS:
This study indicates that UACR may be a useful biomarker for increased risk of osteoporosis in postmenopausal women with type 2 diabetes who have been linked to higher UACR levels.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoporose
/
Proteinúria
/
Doenças Ósseas
/
Doenças Ósseas Metabólicas
/
Densidade Óssea
/
Incidência
/
Prevalência
/
Creatinina
/
Albuminas
/
Falência Renal Crônica
Tipo de estudo:
Estudo de incidência
/
Estudo de prevalência
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Bone Metabolism
Ano de publicação:
2016
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS