Clinical Observation on Shen'ankang Granules for Chronic Renal Failure / 广州中医药大学学报
Article
em Zh
| WPRIM
| ID: wpr-575736
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ABSTRACT
【Objective】To observe the therapeutic effect of Shen'ankang Granules(SG)for chronic renal failure(CRF)and to explore its therapeutic mechanism.【Methods】 Seventy-two CRF patients were equally randomized into groups A and B.The two groups were given oral use of Medicinal Charcoal Tablets and routine supportive and symptomatic treatment,and group A was given SG(mainly composed of Radix Astragali,Radix et Rhizoma Rhei,Herba Epimedii,Radix Notoginseng and Rhizoma Curcumae)additionally.The treatment lasted 8 weeks.The therapeutic effect in the two groups was compared after treatment.Meanwhile,the changes of blood urea nitrogen(BUN),serum creatine(SCr),endogenous creatine clearance rate(Ccr),urinary ?_2 microglobulin(?_2-M)and ?-N-acetyglucosamidase(NAG),as well as changes of serum fibrosis-associated proteins of type Ⅳ collagen(C-Ⅳ),type Ⅲ precollagen(PC-Ⅲ)and laminin(LN)levels were detected.【Results】The total therapeutic effect was 86.11% in group A,higher than 61.11% in group B(P0.05).The differences of serum C-Ⅳ,PC-Ⅲ and LN levels were significant between groups A and B(P
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Índice:
WPRIM
Tipo de estudo:
Clinical_trials
Idioma:
Zh
Revista:
Journal of Guangzhou University of Traditional Chinese Medicine
Ano de publicação:
2000
Tipo de documento:
Article