Antiepilepsy effect of Annao Tablet / 中成药

ABSTRACT

AIM: To study the antiepileptic effect of Annao Tablet (?-asarone extracted from Acorus tatarinowii schott). METHODS: The medicine was administered orally. The effects were observed in mouse's convulsion models induced by picrotoxin, thiosemicarbazide, maximal electroshock seizure (MES) and Penicillin G. RESULTS: Annao Tablet had obvious effect against convulsion induced by picrotoxin and thiosemicarbazide, postponed the delitescence, reduced the convulsion times, prolonged the survival time; antagonized MES. The medicine could depress the epileptic degree, postpone spasm latent period, reduce the wet dog shack times. CONCLUSION: Annao Tablet has obvious antiepileptic effect.