Comparison of the release and percutaneous penetration in vitro between psoralen ointment and gel / 中成药
Chinese Traditional Patent Medicine
;
(12)1992.
Artigo
em Chinês
| WPRIM
| ID: wpr-576465
ABSTRACT
AIM:
To compare the release and percutaneous penetration in vitro among 2 kinds of the psoralen ointments and its gel.METHODS:
Dissolution tester and Franz diffusion cells were adopted as the release and percutaneous penetration in vitro, and HPLC was used to measure the amount of psoralen in the releasing solution, receiving solution and the skin.RESULTS:
The release and percutaneous penetration of psoralen from the 3 kinds of preparation conformed to the zero kinetic equation. The steady-state penetration rate of psoralen in the gel was higher than that of the ointment, and there was no significant difference between 2 kinds of ointments.CONCLUSION:
Gel is a better choice for percutaneous penetration of psoralen.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Traditional Patent Medicine
Ano de publicação:
1992
Tipo de documento:
Artigo
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