Comparison remifentanil and fentanyl in combined anesthesia of gynaecologic laparoscopy / 重庆医科大学学报

ABSTRACT

Objective:The purpose of this study is to evaluate the clinical efficacy of remifentanil combined with proopofol in the course of anesthesia induction and analepsia. Methods: 90 ASAⅠ～Ⅱpatients excision of tumor of the ovary and salphingectomy undergoing gynaecologic laparoscopy were randomly divided into two groupsR group (propofol and vemifentanil n=45) and F group (propofol and fentanil n=45).MAP and HR were observed at the time of anesthesia induction tracheal intubation;the time of spontaneuusly breathing,awakeness,extubation,orientation force and the time of PACU were record;we view the patient of conscious state,cognition functional and the degree of pain;and observe the side effects of nausea and vomitting,intraoperative awareness and degree of patients'satisfaction. Result:There was no significant diference in decrease of two group of MAP in the course of anesthesia. The rate of cardiovascular response to tracheal intubation in F group is higher than that in R group, and hemobynamics was stabler. There was significantly diference in the time of spontaneously breathing,awakeness and extubation. At the time instant extubation and departing PACU were shorter, VAS after extubation 1h in R group was higher than that in F group. There was no significant diference in incidence rate of postoperative nausea and vomitting. Conclusion: Awake qualily of intravenous anesthesia with Propofol and remifentanil was better than that with Propofol and fentanil in excision of tumor of the ovary and salpingectomy undergoing gynaecologic laparoscopy. As half life of remifentanil was short, patients felt pain soon after operation and pestoperative analgesia should be performed promptly.