Study on Pureparation Techniques of Jiawei Sini Granules / 中国中医药信息杂志

ABSTRACT

Objective To optimize the conditions of Jiawei Sini granules by inspecting the macroporous resin adsorption refined methods.Methods Orthogonal design was used with saikosaponin A,paeoniflorin,hesperidin and glycyrrhizin as indicators determined by HPLC.Results The AB-8 macroporous resin,the biggest per gram of resin adsorption capacity were saikosaponin A 2.8 mg,paeoniflorin 62.8 mg,hesperidin 49.6 mg,glycyrrhizin 84.9 mg,with the concentration of durg 0.5 g/mL,the resin column diameter-height ratio of 1∶7 and adsorption velocity of 2(BV/h).Conclusion Macroporous resin adsorption method can be used for refining Jiawei Sini Granules.