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Anoxia-reoxygenation up-regulates transcription of TGF?_1 gene in human umbilical veins endothelial cell line / 重庆医科大学学报
Journal of Chongqing Medical University ; (12)2003.
Artigo em Chinês | WPRIM | ID: wpr-578287
ABSTRACT

Objective:

To investigate the influence of anoxia-reoxygenation on the transcription of TGF?1 gene in Human umbilical veins endothelial cell line(ECV304).

Methods:

Anoxia-reoxygenation model of Human umbilical veins endothelial cell line was established. TGF?1 mRNA was half-quantitatively analyzed by a modified RT-PCR.

Results:

The transcription of TGF?1 mRNA was up-regulated significantly in anoxia-reoxygenation group compared with the control group.

Conclusion:

anoxia-reoxygenation may up-regulate the transcription of TGF?1 gene in human umbilical veins endothelial cell line.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Journal of Chongqing Medical University Ano de publicação: 2003 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Journal of Chongqing Medical University Ano de publicação: 2003 Tipo de documento: Artigo