Effects of selective psychological intervention on T lymphocyte and emotion in patients with breast cancer / 重庆医科大学学报

ABSTRACT

Objective:To study the role of selective psychological intervention on peripheral blood T lymphocyte subtypes and emotion in patients with breast cancer. Methods:Randomized-control study method was adopted. Sixty inpatients with breast cancer were divided into intervention group and control group(30 patients in each group). Patients in both groups received routine chemotherapy and health education while the intervention group also received selective psychological intervention. Psychological intervention methods were selected independently and completed daily by patients in intervention group and completion status was also recorded daily on psycho-treatment form by them. Anxiety and depression of both groups were measured and peripheral blood T lymphocyte subtypes were detected pre- and post-treatment. Results:In intervention group CD3+ CD4+ and the ratio of CD4+/CD8+ of T lymphocyte subtypes were higher,while CD8+ was lower after intervention than that before intervention. A significant difference was also observed compared to that of control group(P