Study of Penehyclidine Hydrochloride as Preoperative Medication in Outpatient / 药物流行病学杂志

ABSTRACT

Objective:To evaluate the effect and safety of penehyrclidine hydrochloride when it was applied preoperatively in outpatient.Method:240 patients were randomly divided into two groups.Group P(120 cases)was treated with penehyclidine hydrochloride 0.5mg before the anesthesia as Group A(120 cases)with Atropine 0.25 mg.Sedation scale was observed just 5 and 15 minutes after drug administration.Analge scale,the degree of the patient's dry-mouth and PONV were also recorded.Time of recovery and leaving were studied too.Result:Group P had significantly better analgesic efficacy than Group A(P0.05).The degree of the patients dry-mouth were statistical difference between 2 group both 15min and 4h postoperation(P