Counteraction of Ganoderma Lucidum Polysaccharide on the Inhibition of Mice Splenocyte Proliferation and IL-1? and IL-2 mRNA Expression Induced by Prostaglandin E2 / 广州中医药大学学报
Journal of Guangzhou University of Traditional Chinese Medicine
;
(6)2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-578821
ABSTRACT
Objective To observe the counteraction of Ganoderma lucidum polysaccharide(GLP) on the inhibition of mice splenocyte proliferation and IL-1? and IL-2 mRNA expression induced by prostaglandin E2(PGE2).Methods Mixed lymphocyte culture reaction(MLR) method was used for the experiment.The lymphocyte proliferation was determined by MTT method,and the levels of IL-1? and IL-2 mRNA expression were evaluated by semi-quantitative reverse transcriptase polymerase chain reaction(RT-PCR).Results After co-culture with PGE2 for 48 hours,the splenocyte proliferation was inhibited to some extent,and the difference was significant when the concentration of PGE2 was over 10?mol/L(P
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DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Guangzhou University of Traditional Chinese Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo
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