Your browser doesn't support javascript.
loading
Pharmacokinetics of Paeonia lacliflora and Glycyrrhiza uralensis Compound / 中成药
Chinese Traditional Patent Medicine ; (12)1992.
Artigo em Chinês | WPRIM | ID: wpr-579357
ABSTRACT

AIM:

To study compatibility rationality of combination of Paeonia lacliflora and Glycyrrhiza uralensis.

METHODS:

The effective combination of paeoniflorin(44% purity),glycyrrhizic acid(50% purity) and liquorice flavones(52% purity),glycyrrhizic acid(50% purity) and liquorice flavones(52% purity) were respectively administered to rats.Pharmacokinetic change of these constituents in rat blood was studied.

RESULTS:

The pharmacokinetic parameters of these constituents in rat blood showed that the increases in AUC and C_(max) of effective combination group were more than that of glycyrrhizic acid group or that of liquorice flavones group.T_(max) of the former was extended with respect to the latters.Clearance of effective combination markedly slowed down.

CONCLUSION:

The effective combination of paeonia lacliflora and Glycyrrhiza uralensis have the advantage of either Paeonia lacliflora or Glycyrrhiza uralensis.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Traditional Patent Medicine Ano de publicação: 1992 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Traditional Patent Medicine Ano de publicação: 1992 Tipo de documento: Artigo